Rhein-Main cancer Retreat 2026
During this year’s 6th Rhein-Main Cancer Retreat in Glashütten, our leukemia research group was prominently represented with five engaging talks, alongside eight poster presentations by our PhD students.
Luca succesfully defends his PhD thesis in Halle
We congratulate Luca Cifarelli for his work and the successful defense of his thesis, exploring TP53 as vulnerability and potential therapeutic applications in NUP98::KDM5A AML.
Sara wins the ASH abstract achievement award
Sara was awarded the ASH abstract achievement award of 2025. She joined the annual ASH meeting to give a talk about her most recent findings.
Prof. Klusmann elected as new chair of the AML-BFM study group
Prof. Klusmann was elected chair of the AML-BFM study group. Here with he will be taking on this great resposibility of leading upcoming clinical trials.
C3OMBAT-AML Event
Also this year the C3OMBAT-AML research teams get together to exchange findings and ideas. Thanking our sponsors of the Hilfe für krebskranke Kinder Frankfurt e. V., which fund us with over 1 Mio € yearly.
Phase III Clinical Trial evaluating CPX-351 for ML-DS
In this multicenter prospective trial, CPX-351 replaced conventional induction therapy aiming to reduce toxicity. This paper includes a retrospective analysis and future outlook.
TP53 pathway as vulnerability in NUP98::KDM5A+ AML
Genomic and proteomic analyses identified critical dependencies, which with pharmacologic inhibition effectively induce apoptosis in NUP98::KDM5A AML models.
DLK1 a novel target in Down Syndrome-Associated AML
DLK1 was found to be a GATA1s-driven leukemia dependency in ML-DS, linking fetal hematopoietic programs to leukemic stemness and refractory disease.
UCT Science Day 2025
This year the UCT Science day took place at the Goethe-University and our team contributed with numerous posters and talks. As usual an excellent event with inisghtful interdisciplinary exchange between Frankfurt and Marburg.
Annual Kind-Phillipp-Meeting in Wilsede 2025
At this years Kind-Philipp-Meeting our team joined with a record breaking 21 talks. David was awarded the Kind-Philipp-Presentation Award for his excellent contribution.