Jan-Henning is an ERC grant holder, Professor, and Director of Pediatrics at the Goethe University Frankfurt.
Dirk is a Max Eder Fellow and Professor at the University Hospital of Halle. He specializes in CRISPR-Cas9 systems and modeling leukemia in mice.
Raj (MSNZ Junior group leader) works on patient-dervied xenograft models of pediatric AML, in vivo non-coding RNA studies, and pre-clinical drug testing.
Daniela (postdoctoral fellow) works on mapping the interactomes of the GATA1 / GATA1s transcription factors.
Hasan (postdoctoral fellow) works on epigenetic profiling of naive and malignant hematopoiesis, and modeling AML progression in primary human stem cells.
Lonneke (PhD student, independent) is investigating interactions within the DLK1-DIO3 non-coding RNA locus in normal and malignant megakaryopoiesis.
Leah (PhD student) is performing CRISPR/Cas9 screens in vitro and in vivo of long non-coding RNAs to characterize the underlying fetal-specific oncogenic trascriptional signature of infant AML.
Anna-Lena (PhD student) is performing CRISPR/Cas9-based screens to repurpose the use of FDA-approved therapeutics in ML-DS patients.
Konstantin (bioinformatical PhD student, independent) works on the discovery of novel fusion transcripts involved in leukemia and performs multi-omic analysis on large patient cohorts.
Luca (PhD student, independent) is modeling de novo translocation-driven leukemogenesis and cooperating mutations using CRISPR-Cas9.
Stephanie (clinical scientist) is working on the ML-DS clinical trial and developing immunotherapeutics for pediatric AML.
Jessica (medical student) is performing CRISPR/Cas9 screen of fetal genes in vitro.
Svetlana (medical student) is performing CRISPR/Cas-based screens of long noncoding RNAs.
Katja (technician) works on projects using CRISPR-Cas9 functional genetics to model AML.
Katharina (technician) supports the in vitro aspect of the non-coding RNA and modeling AML projects.
Franziska (technician) supports the FACS sorting of the ML-DS and AML clinical and research projects.
Lucie (technician) supports the in vitro aspect of all non-coding RNA projects.
Robert (medical student) is performing CRISPR/Cas-based screens of long noncoding RNAs to discover novel contributors to AML pathobiology.
View a list of past lab members.