Prof. Dr. Jan-Henning Klusmann

Jan-Henning is an ERC grant holder, Professor, and Director of Pediatrics at the Goethe University Frankfurt.

Lonneke Verboon

Lonneke (PhD student & Scientific Coordinator) is investigating interactions within the DLK1-DIO3 non-coding RNA locus in normal and malignant megakaryopoiesis.

Dr. Xiaoyan Wei

Postdoctoral Researcher

Anna-Lena Schmell

Anna-Lena (PhD student) is performing CRISPR/Cas9-based screens to repurpose the use of FDA-approved therapeutics in ML-DS patients.

David Groll

David (Phd student) is performing CRISPR/Cas9 screens exploring the fetal origin of leukemias.

 

 

Sònia Cases i Palau

Sònia (PhD student) is studying the interplay between GATA1s and secondary mutations during the progression from TAM into ML-DS.

Nina Murmann

Nina (PhD student) is studying epigenetic regulation in development and leukemia.

Amr Abdrbo

Phd student

Katja Rohde

Katja (Phd student) is investiga-ting the relapse mechanism in children with ML-DS.

Katharina Merkewitz

Katharina (technician) supports the in vitro aspect of the non-coding RNA and modeling AML projects.

Franziska Ganß

Franziska (technician) supports the FACS sorting of the ML-DS and AML clinical and research projects.

Daniel Belzer

Daniel (technician) is working on maintaining a patient derived xenograft biobank for pediatric leukemias.

Victoria Lang

Victoria (technician) is working on identifying and testing novel therapeutic treatment options for acute myeloid leukemia in pediatrics.

Dr. José Gonçalves-Dias

José (bioinformatician) performs multi-omics analysis for decoding the mutational epigenetics landscape of pediatric leukemia.

Konstantin Schuschel

Konstantin (PhD student & bioinformatician) works on the discovery of novel fusion transcripts involved in leukemia and performs multi-omic analysis on large patient cohorts.

Emilia Salzmann-Manrique

Emilia (Biostatistician) works in biomedical statistics and data science, focusing on clinical trial studies and research projects.

Prof. Dr. Dirk Heckl

Dirk is the director of the institute for paediatric haematology and oncology in Frankfurt. He specializes in CRISPR-Cas9 systems and modeling leukemia in mice.

Luca Cifarelli

Luca (PhD student, independent) is modeling de novo translocation-driven leukemogenesis and cooperating mutations using CRISPR-Cas9.

Elif Özcan

Elif (Phd student) is investigating the oncofetal reprogramming in pediatric AML using CRISPR-Cas9 screens.

Xiang Fan

Xiang (PhD student) is performing CRISPR-based screens to study the potential RBP targets in cooperation with EZH2 in leukemogenesis.

Johannes Haas

Phd student

 

 

Leonie Mair

Phd student

Sabrina Schuster

Phd student

Dr. med. Celia Kaffenberger

Dr. med. Celia Kaffenberger (Clinician Scientist) explores innovative strategies to enhance immune-based therapies in pediatric AML.

Shaole Song

technican

Dr. Eva Rettinger

Group leader

Elisa Hopke

Phd Student

Max Lürbke Franke

Medical Student

Dr. Raj Bhayadia

Raj (MSNZ Junior group leader) works on patient-dervied xenograft models of pediatric AML, in vivo non-coding RNA studies, and pre-clinical drug testing.

Leah Schüler

Leah (PhD student) is performing CRISPR/Cas9 screens in vitro and in vivo of long non-coding RNAs to characterize the underlying fetal-specific oncogenic trascriptional signature of infant AML.

Robert Winkler

Robert (clinical scientist) is performing CRISPR/Cas-based screens of long noncoding RNAs to discover novel contributors to AML pathobiology.

Stephanie Laszig

Stephanie (clinical scientist) is working on the ML-DS clinical trial and developing immunotherapeutics for pediatric AML.

Dr. Hannah Uckelmann

Hannah (Max-Eder junior research group leader) works on NPM1c-driven leukemogenesis with focus on novel therapeutic therapies in NPM1 mutant AML.

Sara Gama

Sara (PhD student) works on NPM1c-driven leukemogenesis with focus on novel therapeutic therapies in NPM1 mutant AML.

Hannah Gonzalez

Hannah (PhD student) examines the role of the nuclear export factor XPO1 on chromatin in NPM1c-driven AML.

Arezo Javadpoor

Arezo (PhD student) works on exploring the epigenetic regulation of leukemia development.

Dr. Marit Willemijn Vermunt

Marit’s Max-Eder junior research group investigates CTCF, antisense transcription and DNA methylation in cancer.

Zijin Zhang

Zijin (Phd Student) works on the identification of antisense transcripts, and investigates their role in pediatric leukemia.

Tairan Zhong

Tairan (PhD student) studies clonal evolution and therapy resistance in leukemia.

Gemma Hughes-Waldon

Gemma (technican) supports tissue culture and wet lab experiments that are centered around CTCF and (noncoding) RNA.

Lavinia Grob

Lavinia (technican) supports tissue culture and molecular studies focused on antisense transcription and the role of transient enhancers in erythroid differentition.

Dr. Stephan Emmrich

Stephan (Junior group leader) is working to direct a bioinformatics hub and to establish a team working on HSC biology & how to boost them.