Pediatric and Experimental Hematology
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Prof. Dr. Jan-Henning Klusmann
Jan-Henning is an ERC grant holder, Professor, and Director of Pediatrics at the Goethe University Frankfurt.
Prof. Dirk Heckl
Dirk is the director of the institute for paediatric haematology and oncology in Frankfurt. He specializes in CRISPR-Cas9 systems and modeling leukemia in mice.
Dr. Raj Bhayadia
Raj (MSNZ Junior group leader) works on patient-dervied xenograft models of pediatric AML, in vivo non-coding RNA studies, and pre-clinical drug testing.
Dr. Hannah Uckelmann
Hannah (junior group leader) works on NPM1c-driven leukemogenesis with focus on novel therapeutic therapies in NPM1 mutant AML.
Dr. Marit Willemijn Vermunt
Marit (junior group leader) works on transcriptional regulation in normal as well as malignant hematopoiesis with a focus on the interplay between CTCF and noncoding RNAs.
Dr. Hasan Issa
Hasan (postdoctoral fellow) works on epigenetic profiling of naive and malignant hematopoiesis, and modeling AML progression in primary human stem cells.
Lonneke Verboon
Lonneke (PhD student, independent) is investigating interactions within the DLK1-DIO3 non-coding RNA locus in normal and malignant megakaryopoiesis.
Anna-Lena Schmell
Anna-Lena (PhD student) is performing CRISPR/Cas9-based screens to repurpose the use of FDA-approved therapeutics in ML-DS patients.
Leah Schüler
Leah (PhD student) is performing CRISPR/Cas9 screens in vitro and in vivo of long non-coding RNAs to characterize the underlying fetal-specific oncogenic trascriptional signature of infant AML.
Sònia Cases i Palau
Sònia (PhD student) is studying the interplay between GATA1s and secondary mutations during the progression from TAM into ML-DS.
Sara Gama
Sara (PhD student) works on NPM1c-driven leukemogenesis with focus on novel therapeutic therapies in NPM1 mutant AML.
David Groll
David (Phd student) is performing CRISPR/Cas9 screen of fetal genes in vitro.
Luca Cifarelli
Luca (PhD student, independent) is modeling de novo translocation-driven leukemogenesis and cooperating mutations using CRISPR-Cas9.
Konstantin Schuschel
Konstantin (bioinformatical PhD student, independent) works on the discovery of novel fusion transcripts involved in leukemia and performs multi-omic analysis on large patient cohorts.
José Gonçalves Dias
José (Information) is performing RNA-sequencing and multiomics analysis.
Stephanie Laszig
Stephanie (clinical scientist) is working on the ML-DS clinical trial and developing immunotherapeutics for pediatric AML.
Jessica Santosa Hidajat
Jessica (medical student) is performing CRISPR/Cas9 screen of fetal genes in vitro.
Robert Winkler
Robert (medical student) is performing CRISPR/Cas-based screens of long noncoding RNAs to discover novel contributors to AML pathobiology.
Katja Menge
Katja (technician) works on projects using CRISPR-Cas9 functional genetics to model AML.
Katharina Merkewitz
Katharina (technician) supports the in vitro aspect of the non-coding RNA and modeling AML projects.
Kenza Benhassine
Kenza (technician) supports the in vitro aspect of the non-coding RNA and modeling AML projects.
Niko Vadillo Schönhaber
Nico (technician) supports the in vitro aspect of the non-coding RNA and modeling AML projects.
Michelle Christmann
Michelle (technician) supports the in vitro aspect of the non-coding RNA and modeling AML projects.
Franziska Ganß
Franziska (technician) supports the FACS sorting of the ML-DS and AML clinical and research projects.
Alumni
View a list of past lab members.