Pediatric and Experimental Hematology

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Prof. Dr. Jan-Henning Klusmann

Jan-Henning is an ERC grant holder, Professor, and Director of Pediatrics at the Goethe University Frankfurt.

Prof. Dirk Heckl

Dirk is a Max Eder Fellow and Professor at the University Hospital of Halle. He specializes in CRISPR-Cas9 systems and modeling leukemia in mice.

Dr. Raj Bhayadia

Raj (MSNZ Junior group leader) works on patient-dervied xenograft models of pediatric AML, in vivo non-coding RNA studies, and pre-clinical drug testing.

Dr. Marit Willemijn Vermunt

Marit (junior group leader) works on transcriptional regulation in normal as well as malignant hematopoiesis with a focus on the interplay between CTCF and noncoding RNAs.

Dr. Daniela Bräuer-Hartmann

Daniela (postdoctoral fellow) works on mapping the interactomes of the GATA1 / GATA1s transcription factors.

Dr. Hasan Issa

Hasan (postdoctoral fellow) works on epigenetic profiling of naive and malignant hematopoiesis, and modeling AML progression in primary human stem cells.

Lonneke Verboon

Lonneke (PhD student, independent) is investigating interactions within the DLK1-DIO3 non-coding RNA locus in normal and malignant megakaryopoiesis.

Leah Schüler

Leah (PhD student) is performing CRISPR/Cas9 screens in vitro and in vivo of long non-coding RNAs to characterize the underlying fetal-specific oncogenic trascriptional signature of infant AML.

Anna-Lena Schmell

Anna-Lena (PhD student) is performing CRISPR/Cas9-based screens to repurpose the use of FDA-approved therapeutics in ML-DS patients.

Konstantin Schuschel

Konstantin (bioinformatical PhD student, independent) works on the discovery of novel fusion transcripts involved in leukemia and performs multi-omic analysis on large patient cohorts.

Luca Cifarelli

Luca (PhD student, independent) is modeling de novo translocation-driven leukemogenesis and cooperating mutations using CRISPR-Cas9.

José Gonçalves Dias

José (Bioinformation) is performing RNA-sequencing and multiomics analysis.

Stephanie Laszig

Stephanie (clinical scientist) is working on the ML-DS clinical trial and developing immunotherapeutics for pediatric AML.

Jessica Santosa Hidajat

Jessica (medical student) is performing CRISPR/Cas9 screen of fetal genes in vitro. 

Katja Menge

Katja (technician) works on projects using CRISPR-Cas9 functional genetics to model AML.

Katharina Merkewitz

Katharina (technician) supports the in vitro aspect of the non-coding RNA and modeling AML projects.

Kenza Benhassine

Kenza (technician) supports the in vitro aspect of the non-coding RNA and modeling AML projects.

Franziska Kalensee

Franziska (technician) supports the FACS sorting of the ML-DS and AML clinical and research projects.

Lucie Gack

Lucie (technician) supports the in vitro aspect of all non-coding RNA projects.

Robert Winkler

Robert (medical student) is performing CRISPR/Cas-based screens of long noncoding RNAs to discover novel contributors to AML pathobiology.


View a list of past lab members.