Two of our papers went online this week! 2) A review article on the regulatory roles of long noncoding RNAs in acute myeloid leukemia, including an updated catalog of functionally defined examples.
Another excellent PhD defense this year! Congratulations to Dr. rer. nat. Sofia Gialesaki, who graduated with a summa cum laude in June - among the first from the PhD program's entering class of 2015!
We are very proud of Sofia, who won a YoungEHA Best Abstract Award and presented the RUNX1 story to thousands during the EHA 2019 Presidential Symposium today. Yay Sofia!
Following an excellent thesis defense, Dr. rer. nat. Maurice Labuhn graduated with a summa cum laude from the HBRS Molecular Medicine PhD program. Many congratulations!
The TMD Prevention 2007 trial found that low-dose cytarabine treatment reduced mortality in TMD patients. However, this therapy did not prevent disease progression to ML-DS.
We have an open position for a skilled and dedicated postdoc in our new laboratory in Halle. Applications are welcome until the end of February. See the full post for more details.
The proceeds from this year's Charity Day were given to Pediatrics I of the Universitätsklinikum Halle. The funds will support research on leukemia in children with Down sydrome.
CRISPR-Cas9 genome editing was used to induce GATA1s in HSPCs of fetal, neonatal, and adult origin, leading to distinct ontogeny-specific disturbances in megakaryopoiesis and erythropoiesis.
The tumor suppressor miR-193b is downregulated in AML. Expression induces leukemic cell death through repression of MAPK signalling, making miR-193b a candidate for RNA-based therapy.
Introducing CRISPRater: a tool for more efficiently selecting effective sgRNAs in CRISPR-Cas9 applications. In addition, we provide a meta-analysis and individual evaluation of five current prediction algorithms.