Myeloid leukemia vulnerabilities embedded in long non-coding RNA locus MYNRL15
Publication alert: The identification of long non-coding RNA locus MYNRL15 shows novel therapeutic potential in AMLs with various genetic backgrounds.
Commentary: IRAK1/4 inhibitors in MDS/AML
In this commentary Dr. Uckelmann and Prof. Klusmann point out recent findings that highlight the therapeutic potential of cotargeting IRAK1 and IRAK4.
Influenza A (H1N1) virus induced long-term remission in a refractory acute myeloid leukaemia
In our commentary we highlight a special case of refractory AML, which went into complete remission after Influenza A infection.
Preclinical testing of miR-193b-3p mimic in AML
Today the work of our PostDoc Dr. Hasan Issa and colleagues was publishe in Leukemia. It presents the anti-leukemic effects of microRNA-193b-3p and its clincial potential.
RUNX1 publication choosen as Plenary Paper and for Podcast Feature
Our latest Paper was chosen as plenary paper in this weeks Issue of Blood. Along side it is also available as audio summary on the latest Blood Podcast.
RUNX1 isoform disequilibrium promotes the development of ML-DS
Our latest BLOOD paper unravels the importance of RUNX1 isoform equilibrium and its interaction with the oncogenic players GATA1s and the MYC:MAX complex.