Pediatric and Experimental Hematology
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Prof. Dr. Jan-Henning Klusmann
Jan-Henning is an ERC grant-holder, Professor, and Director of Pediatrics & Pediatric Oncology at the University Hospital of Halle.
Prof. Dirk Heckl
Dirk is a Max Eder Fellow and Professor at the University Hospital of Halle. He specializes in CRISPR-Cas9 systems and modeling leukemia in mice.
PD. Dr. Jessica Höll
Jessica is a physician and junior group leader at the University Hospital of Halle. Her research centers on the role of RNA-binding proteins in leukemia.
Dr. Raj Bhayadia
Raj (postdoctoral fellow) works on patient-dervied xenograft models of pediatric AML, in vivo non-coding RNA studies, and pre-clinical drug testing.
Dr. Daniela Bräuer-Hartmann
Daniela (postdoctoral fellow) works on mapping the interactomes of the GATA1 / GATA1s transcription factors.
Dr. Hasan Issa
Hasan (postdoctoral fellow) works on delivering lipid nanoparticle-based oligonucleotides into AML cells, towards RNA-centered therapies.
Oriol Alejo
Oriol (PhD student, independent) is investigating the interactive genetic network of the stem cell microRNA cluster miR-99a/105~125b.
Michelle Ng
Michelle (PhD student, HBRS Molecular Medicine) is using CRISPR-based perturbation approaches to interrogate long non-coding RNAs in AML.
Lonneke Verboon
Lonneke (PhD student, independent) is investigating interactions within the DLK1-DIO3 non-coding RNA locus in normal and malignant megakaryopoiesis.
Konstantin Schuschel
Konstantin (PhD student, independent) is screening RNA-binding proteins for novel contributors to acute leukemia pathogenesis.
Luca Cifarelli
Luca (PhD student, independent) is modeling de novo translocation-driven leukemogenesis and cooperating mutations using CRISPR-Cas9.
Kristof Meier
Kristof (PhD student, independent) is screening genes encoding drug-targetable proteins, towards identifying novel therapy options for AML.
Robert Winkler
Robert (medical student, UKH) is performing CRISPR/Cas-based screens of long noncoding RNAs to discover novel contributors to AML pathobiology.
Christoph Beyer
Christoph (medical student, UKH) is performing histone and transcription factor profiling in order to map the epigenetic landscapes of AML cells.
Lisa Dietrich
Lisa (technician) assists with the GATA1 / GATA1s / RUNX1 interactome projects.
Lucie Gack
Lucie (technician) supports the in vitro aspect of all non-coding RNA projects.
Katja Menge
Katja (technician) works on projects using CRISPR-Cas9 functional genetics to model AML.
Alumni
View a list of past lab members.
Endogenous retroviruses in cancer and autoimmunity
Apl. Prof. Martin S. Staege
Martin is a molecular biologist and immunologist. He researches endogenous retroviruses and gene expression in cancer and autoimmunity.
Dr. Kristina Engel
Kristina (postdoctoral fellow) works on the characterization of endogenous retroviruses in tumor cells and autoimmune diseases.
Anna Krüger
Anna (PhD student) works on the characterization of endogenous retroviruses in tumor cells and autoimmune diseases.
Lisa Wieland
Lisa (PhD student) studies the expression of endogenous retroviruses (ERVs) and their interaction with Epstein-Barr virus.
Ines Volkmer
Ines (technician) supports all cell culture experiments and gene expression analyses.