Pediatric and Experimental Hematology

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Prof. Dr. Jan-Henning Klusmann

Jan-Henning is an ERC grant-holder, Professor, and Director of Pediatrics & Pediatric Oncology at the University Hospital of Halle.

Prof. Dirk Heckl

Dirk is a Max Eder Fellow and Professor at the University Hospital of Halle. He specializes in CRISPR-Cas9 systems and modeling leukemia in mice.

Dr. Raj Bhayadia

Raj (postdoctoral fellow) works on patient-dervied xenograft models of pediatric AML, in vivo non-coding RNA studies, and pre-clinical drug testing.

Dr. Daniela Bräuer-Hartmann

Daniela (postdoctoral fellow) works on mapping the interactomes of the GATA1 / GATA1s transcription factors.

Dr. Hasan Issa

Hasan (postdoctoral fellow) works on delivering lipid nanoparticle-based oligonucleotides into AML cells, towards RNA-centered therapies.

Oriol Alejo

Oriol (PhD student, independent) is investigating the interactive genetic network of the stem cell microRNA cluster miR-99a/105~125b.

Michelle Ng

Michelle (PhD student, HBRS Molecular Medicine) is using CRISPR-based perturbation approaches to interrogate long non-coding RNAs in AML.

Lonneke Verboon

Lonneke (PhD student, independent) is investigating interactions within the DLK1-DIO3 non-coding RNA locus in normal and malignant megakaryopoiesis.

Konstantin Schuschel

Konstantin (PhD student, independent) is screening RNA-binding proteins for novel contributors to acute leukemia pathogenesis.

Luca Cifarelli

Luca (PhD student, independent) is modeling de novo translocation-driven leukemogenesis and cooperating mutations using CRISPR-Cas9.

Kristof Meier

Kristof (PhD student, independent) is screening genes encoding drug-targetable proteins, towards identifying novel therapy options for AML.

Robert Winkler

Robert (medical student, UKH) is performing CRISPR/Cas-based screens of long noncoding RNAs to discover novel contributors to AML pathobiology.

Christoph Beyer

Christoph (medical student, UKH) is performing histone and transcription factor profiling in order to map the epigenetic landscapes of AML cells.

Lisa Dietrich

Lisa (technician) assists with the GATA1 / GATA1s / RUNX1 interactome projects.

Lucie Gack

Lucie (technician) supports the in vitro aspect of all non-coding RNA projects.

Katja Menge

Katja (technician) works on projects using CRISPR-Cas9 functional genetics to model AML.

Alumni

View a list of past lab members.