Pediatric and Experimental Hematology
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Prof. Dr. Jan-Henning Klusmann
Jan-Henning is an ERC grant-holder, Professor, and Director of Pediatrics & Pediatric Oncology at the University Hospital of Halle.
Prof. Dirk Heckl
Dirk is a Max Eder Fellow and Professor at the University Hospital of Halle. He specializes in CRISPR-Cas9 systems and modeling leukemia in mice.
PD. Dr. Jessica Höll
Jessica is a physician and junior group leader at the University Hospital of Halle. Her research centers on the role of RNA-binding proteins in leukemia.
Dr. Raj Bhayadia
Raj (postdoctoral fellow) works on patient-dervied xenograft models of pediatric AML, in vivo non-coding RNA studies, and pre-clinical drug testing.
Dr. Daniela Bräuer-Hartmann
Daniela (postdoctoral fellow) works on mapping the interactomes of the GATA1 / GATA1s transcription factors.
Dr. Hasan Issa
Hasan (postdoctoral fellow) works on delivering lipid nanoparticle-based oligonucleotides into AML cells, towards RNA-centered therapies.
Oriol Alejo
Oriol (PhD student, independent) is investigating the interactive genetic network of the stem cell microRNA cluster miR-99a/105~125b.
Michelle Ng
Michelle (PhD student, HBRS Molecular Medicine) is using CRISPR-based perturbation approaches to interrogate long non-coding RNAs in AML.
Lonneke Verboon
Lonneke (PhD student, independent) is investigating interactions within the DLK1-DIO3 non-coding RNA locus in normal and malignant megakaryopoiesis.
Sofia Gialesaki
Sofia (PhD student, HBRS Molecular Medicine) is studying the interplay between chromosome 21 genes and GATA1s in Down syndrome AML.
Dorit Schneider
Dorit (PhD student, HBRS Molecular Medicine) is studying the deregulated network in Ezh2-mutated AML using state-of-the-art CRISPR-Cas9 technology.
David Mir-Salim
David (medical student, UKH) is performing drug testing on patient-dervied xenografts in vivo to find new potential therapies for childhood AML.
Luca Cifarelli
Luca (PhD student, independent) is modeling de novo translocation-driven leukemogenesis and cooperating mutations using CRISPR-Cas9.
Konstantin Schuschel
Konstantin (PhD student, independent) is screening RNA-binding proteins for novel contributors to acute leukemia pathogenesis.
Lucie Gack
Lucie (technician) supports the in vitro aspect of all non-coding RNA projects.
Lisa Dietrich
Lisa (technician) assists with the GATA1 / GATA1s / RUNX1 interactome projects.
Katja Menge
Katja (technician) works on projects using CRISPR-Cas9 functional genetics to model AML.
Endogenous retroviruses in cancer and autoimmunity
Apl. Prof. Martin S. Staege
Martin is a molecular biologist and immunologist. He researches endogenous retroviruses and gene expression in cancer and autoimmunity.
Dr. Kristina Engel
Kristina (postdoctoral fellow) works on the characterization of endogenous retroviruses in tumor cells and autoimmune diseases.
Anna Krüger
Anna (PhD student) works on the characterization of endogenous retroviruses in tumor cells and autoimmune diseases.
Lisa Wieland
Lisa (PhD student) studies the expression of endogenous retroviruses (ERVs) and their interaction with Epstein-Barr virus.
Ines Volkmer
Ines (technician) supports all cell culture experiments and gene expression analyses.