Jan-Henning is an ERC grant holder, Professor, and Director of Pediatrics at the Goethe University Frankfurt.
Dirk is a Max Eder Fellow and Professor at the University Hospital of Halle. He specializes in CRISPR-Cas9 systems and modeling leukemia in mice.
Raj (postdoctoral fellow) works on patient-dervied xenograft models of pediatric AML, in vivo non-coding RNA studies, and pre-clinical drug testing.
Daniela (postdoctoral fellow) works on mapping the interactomes of the GATA1 / GATA1s transcription factors.
Hasan (postdoctoral fellow) works on delivering lipid nanoparticle-based oligonucleotides into AML cells, towards RNA-centered therapies.
Oriol (postdoctoral fellow) is investigating the interactive genetic network of the stem cell microRNA cluster miR-99a/105~125b.
Michelle (postdoctoral fellow) is leveraging CRISPR-based perturbation approaches to interrogate long non-coding RNA functions in AML.
Lonneke (PhD student, independent) is investigating interactions within the DLK1-DIO3 non-coding RNA locus in normal and malignant megakaryopoiesis.
Konstantin (PhD student, independent) is screening RNA-binding proteins for novel contributors to acute leukemia pathogenesis.
Luca (PhD student, independent) is modeling de novo translocation-driven leukemogenesis and cooperating mutations using CRISPR-Cas9.
Christoph (medical student, UKH) is performing histone and transcription factor profiling in order to map the epigenetic landscapes of AML cells.
Robert (medical student, UKH) is performing CRISPR/Cas-based screens of long noncoding RNAs to discover novel contributors to AML pathobiology.
Lisa (technician) assists with the GATA1 / GATA1s / RUNX1 interactome projects.
Katja (technician) works on projects using CRISPR-Cas9 functional genetics to model AML.
Lucie (technician) supports the in vitro aspect of all non-coding RNA projects.
View a list of past lab members.